TABLE 5.
Nonclinical factors (adjusted for clinical factors) that are determinants of choice of therapy
| Factor | C → LR vs. LR
|
PC vs. LR
|
PC vs. C → LR
|
P | |||
|---|---|---|---|---|---|---|---|
| OR | 95 % CI | OR | 95 % CI | OR | 95 % CI | ||
| Practice type | |||||||
| Private | Ref. | Ref. | Ref. | 0.95 | |||
| Academic | 1.08 | 0.67–1.74 | 1.09 | 0.53–2.23 | 1.01 | 0.58–1.75 | |
| Years in practice (years) | |||||||
| <10 | Ref. | Ref. | Ref. | 0.005 | |||
| ≥10 | 0.70 | 0.46–1.06 | 1.36 | 0.70–2.66 | 1.94 | 1.18–3.18 | |
| Fellowship training | |||||||
| Hepato-pancreato-biliary or transplantation | Ref. | Ref. | Ref. | <0.001 | |||
| Surgical oncology | 2.53 | 1.66–3.87 | 4.15 | 2.07–8.29 | 1.64 | 0.92–2.91 | |
| No fellowship training | 2.06 | 0.95–4.49 | 2.94 | 0.81–10.7 | 1.43 | 0.53–3.81 | |
| Proportion of CLM cases discussed at multidisciplinary tumor board (%) | |||||||
| <50 | Ref. | Ref. | Ref. | 0.03 | |||
| ≥50 | 1.16 | 0.75–1.81 | 0.58 | 0.30–1.13 | 0.50 | 0.30–0.84 | |
| No. of patients monthly evaluated for CLM | |||||||
| <8 | Ref. | Ref. | Ref. | 0.44 | |||
| ≥8 | 1.03 | 0.66–1.60 | 0.72 | 0.34–1.56 | 0.70 | 0.40–1.23 | |
LR immediate liver resection, C → LR preoperative chemotherapy followed by surgery, PC palliative chemotherapy, OR odds ratio, CI confidence interval, Ref. referent, CLM colon cancer liver metastasis