Table 2.
Biochemical quantifications of glutathione, myeloperoxidase (MPO), and alkaline phosphatase in the colon of the animals submitted to the acute colitis model.
| Glutathione (nmol/g) | MPO (U/g) | Alkaline phosphatase (mU/mg of protein) | |
|---|---|---|---|
| Non-colitic | 1,555.75 ± 107.83* | 16.98 ± 4.63* | 8.43 ± 0.79* |
| TNBS control | 954.73 ± 69.74 | 1,780.19 ± 263.77 | 17.21 ± 1.16 |
| EC 5 | 1,035.49 ± 72.95 | 1,975.90 ± 294.86 | 20.78 ± 1.98 |
| EC 10 | 1,176.55 ± 46.34* | 1,876.74 ± 243.27 | 17.83 ± 1.30 |
| EC 25 | 1,130.95 ± 42.46 | 1,973.38 ± 178.27 | 20.04 ± 2.71 |
| EC 50 | 1,127.25 ± 35.36 | 1,806.57 ± 219.35 | 20.47 ± 2.02 |
| Sulfasalazine | 1,104.60 ± 22.33 | 1,814.55 ± 214.46 | 20.49 ± 2.01 |
Results are mean ± E.P.M. ANOVA-Dunnet comparing to the TNBS control group, *P < 0.05. n = 5–8. EC 5 to 50: Epicatechin, doses 5 to 50 mg/kg.