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. Author manuscript; available in PMC: 2013 Jan 16.
Published in final edited form as: Adv Protein Chem Struct Biol. 2012;87:363–389. doi: 10.1016/B978-0-12-398312-1.00012-3

Fig. 2.

Fig. 2

Chemical perturbations upon ligand binding for PKA-CWT and PKA-CY204A. The binding of nucleotide and substrate indicates attenuated local and long-range (allosteric) perturbations for PKA-CY204A.