TABLE 2.
Variables Explaining Biological Response (Salivary Cortisol Responsivity)
| Explanatory variable | Model coefficient (SE)a | % Change (95% CI)b | p |
|---|---|---|---|
| Parent’s perception of how distressed child becomes in the morning of the intravenous insertion | 0.145 (0.037) | 15.6% (7.4% to 24.5%) | .0001 |
| Diagnosis of ADHD | −1.181 (0.294) | −69.3% (−45.2% to −82.8%) | <.0001 |
| Diagnosis of anxiety disorder | 1.161 (0.417) | 219% (40% to 527%) | .006 |
| Time child finds out about the intravenous procedure (vs. < 24 hours) | |||
| At visit | 0.619 (0.223) | 85.7% (19.7% to 188.0%) | .006 |
| Greater than 24 hours | 0.418 (0.192) | 50.3% (3.0% to 119.5%) | .035 |
| Distraction Coaching Index | |||
| <10 (vs. >20) | 0.270 (0.165) | 30.9% (−5.4% to 81.3%) | .104 |
| 10–20 (vs. >20) | 0.394 (0.213) | 48.4% (−2.6% to 125.9%) | .066 |
Note. Cortisol Responsivity = (% change from baseline after the intravenous insertion); R2 = 19.7%. CI = confidence interval; ADHD = attention deficit hyperactivity disorder; IV = intravenous.
a
The model coefficients are for natural log transform of cortisol as the dependent variable.
b
For the continuous explanatory variables, this is the % change for every one-unit increase in the explanatory variable.