Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The effect of COMT inhibition on spatial novelty preference. Novelty preference was significantly increased in tolcapone-treated rats (closed bar; n=20), compared with those vehicle-treated (open bars; n=20). Non-injected controls (cross-hatched bars; n=21) showed intermediate levels of performance. Bars indicate means ± SEMs; chance performance (50%) is indicated by the dashed line. *p<0.05.
