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The interrelationship between methylenetetrahydrofolate reductase (MTHFR) genotype, riboflavin and folic acid with respect to (a) cytosine-phosphate-guanosine dinucleotide (CpG) methylation and uracil in DNA; (b) initiation of cancer caused by CpG hypomethylation. The level of riboflavin and folic acid depends on supplementation [3], modified.
