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. 2012 Dec 6;9(12):4486–4497. doi: 10.3390/ijerph9124486

Table 3.

A summary of the correlation1 between hair toxic metals concentrations and ASD severity2.

Hair Metal Type Rho Rho 95% Confidence Interval p-value
Arsenic (As) −0.13 −0.56 to 0.36 0.62
Lead (Pb) −0.31 −0.68 to 0.18 0.21
Mercury (Hg) 0.58 0.15 to 0.82 0.013 3
Cadmium (Cd) −0.33 −0.69 to 0.16 0.18
Chromium (Cr) 0.30 −0.19 to 0.67 0.22
Cobalt (Co) −0.34 −0.69 to 0.15 0.17
Nickel (Ni) −0.10 −0.54 to 0.39 0.70
Manganese (Mn) −0.11 −0.55 to 0.37 0.65
Aluminum (Al) 0.08 −0.40 to 0.53 0.75
Tin (Sn) −0.14 −0.57 to 0.35 0.59
Uranium (U) 0.23 −0.27 to 0.63 0.36

1 The Spearman’s rank correlation test statistic was utilized; 2 ASD severity was measured using the Childhood Autism Rating Scale (CARS) score; 3 Eliminating the anomalous highest hair Hg data point (CARS score = 43, hair mercury level = 4.4 µg of Hg per g of hair) from the sample set examined still revealed a significant correlation (Rho = 0.57, Rho 95% confidence interval = 0.12 to 0.82, p = 0.018) between hair Hg concentrations and ASD severity.