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Calcium, calcium-calmodulin, and PFK-1 (de)activation kinetics. Predictions of (de)activation kinetics of PFK-1 (black), calcium-calmodulin kinetics (red) and calcium kinetics (bue) for 10 Hz (A) and 40 Hz (B). For illustrative purposes the concentrations of calcium-calmodulin and calcium were scaled to the same order of magnitude as the fraction activated PFK-1. For calcium-calmodulin 1 unit corresponds to 0.040 μM and for calcium 1 unit corresponds to 30 μM.
