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. 2012 Dec 17;11:422. doi: 10.1186/1475-2875-11-422

Table 1.

Summary of the impact of combination therapy, MFT and sequential application on useful therapeutic life and the spread of multi-resistant genotypes assuming drug usage typical in control scenarios

Policy Impact
Sequential application
Medium useful therapeutic life
 
Low multi-drug resistance
MFT
Long useful therapeutic life
 
Low multi-drug resistance
Combination therapy
Longest useful therapeutic life
  Extreme increase in multi-drug resistance