Table 4.
Various antigenically important amino acid/motifs/deletions observed in different gene segments of Pakistani H5N1 viruses
| HPAI AA Motif | HA 222 | HA 224 |
NA Deletion 49-68 |
NA 275 | MP 26 | MP 27 | MP 30 | MP 31 | MP 34 | NS Deletion 80-84 | NS 149 | PDZ Binding domain | PB2 627 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ck/Rawalakot/2441/06 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
L |
V |
A |
S |
G |
YES |
A |
ESKV |
K |
| Ck/Sihala/3303/06 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
L |
V |
A |
S |
G |
YES |
A |
ESKV |
K |
| Ck/Laore/3320/06 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
L |
V |
A |
S |
G |
YES |
A |
ESKV |
K |
| Gs/Lahore/3321/06 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Pck/Mansehra/7558/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Gs/Islamabd/7757/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Tk/Islamabad/7871/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Tk/Islamabad/7873/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Crow/Peshawar/7914/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Pck/Chakshahzad/9238/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Ck/Mansehra/10337/07 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
- |
- |
- |
- |
| Ck/Karachi/520/08 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
YES |
A |
ESKV |
- |
| Ck/Lahore/610/08 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
YES |
A |
ESKV |
- |
| Ck/Karachi/612/08 |
PQGERRRKKRGLF |
Q |
G |
YES |
H |
- |
- |
- |
- |
- |
YES |
A |
ESKV |
- |
| Crow/Karachi/11672/08 | PQGERRRKKRGLF | Q | G | YES | H | - | - | - | - | - | YES | A | ESKV | - |
Ck: Chicken, Gs: Goose, Ty: Turkey, Cw: Crow, Pk: Peacock, Pak: Pakistan.
Not done/Data not available.