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Supernatant derived from MAPC:splencocyte co-cultures attenuates LPS induced proliferation. There was a significant reduction in proliferation of microglia as determined by absorbance of MTS (P ≤0.01: n = 8) in the microglia treated with supernatant derived from MAPC:splenocyte co-culture when compared to splenocyte only culture. ** represents P <0.01. LPS, lipopolysaccharide; MAPC, multipotent adult progenitor cell; MTS.
