Table 2.
Summary of baseline characteristics and treatment outcomes for development and validation cohort
| Characteristic |
Development cohort |
Validation cohort |
P |
|---|---|---|---|
| N = 381 | N = 822 | ||
| Age (years) |
34.8 +/− 4.48 |
35.3 +/− 4.28 |
Ns |
| BMI (kg/m2) |
24 +/− 5.8 |
24.6 +/− 4.30 |
<.05 |
| AMH (ng/ml) |
1.3 (0.03, 13.8) |
2.16 (0.02, 38.6) |
<.05 |
| Duration of infertility (years) |
2.8 +/− 1.7 |
2.49 +/− 2.36 |
<.05 |
| Cause of infertility | |||
| Combination of cause |
67 (17.5%) |
71 (8.6%) |
<.05 |
| Endometriosis |
45 (11.8%) |
39 (4.7%) |
<.05 |
| Idiopathic |
140 (36.8%) |
270 (32.8%) |
Ns |
| Male factor |
123 (32.4%) |
285 (34.7%) |
Ns |
| Ovulatory |
82 (21.5%) |
35 (4.3%) |
<.05 |
| Tubal disease |
57 (15.0%) |
122 (14.8%) |
Ns |
| Treatment outcomes: | |||
| Duration of stimulation (days) |
12.8 +/− 2.8 |
10.4 +/− 2.11 |
<.05 |
| Dose (IU) |
205 +/− 58.6 |
216 +/− 59.0 |
<.05 |
| Oocytes per patient |
8.5 +/− 5.1 |
7.99 +/− 4.71 |
Ns |
| Embryo transfers performed |
347 (91.1%) |
713 (86.7%) |
<.05 |
| Number of embryos transferred: | |||
| 0 |
34 (9.8%) |
109 (13.3%) |
Ns |
| 1 |
8 (2.3%) |
127 (15.5%) |
<.05 |
| 2 |
83 (23.9%) |
534 (65.0%) |
<.05 |
| 3 |
256 (73.8%) |
52 (6.3%) |
<.05 |
| Clinical pregnancy |
127 (33.3%) |
264 (32.1%) |
Ns |
| Live birth | 101 (26.5%) | 242 (29.4%) | Ns |
Values are presented as mean +/− SD, median (range) or n (%).
Ns: non-significant.