Figure 3.

Formalin-induced pain behaviors and brain lesion maps associated with rats with caudal ACC lesions (n = 8) and caudal ACC sham lesions (n = 11). Data are represented as mean ± SEM. Acute formalin-induced nociceptive scores are shown in A. Magnitude of CPA scores are shown in B. Representations of the largest and smallest lesions in the caudal ACC lesion group are shown in C. Mean “percent damage” calculations for each hemisphere and a bilateral mean for each experimental group are as follows: left hemisphere, 82% ± 5%; right hemisphere, 67% ± 5%; mean, 74% ± 4%. Caudal ACC lesions had no effect on either acute formalin-induced nociceptive behaviors (A) or F-CPA (B).