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. 2013 Jan 16;8(1):e52840. doi: 10.1371/journal.pone.0052840

Figure 5. Effect of FC injection into TG on masseter muscle activity and GFAP and pERK-IR cell expression.

Figure 5

A and B: Typical example of masseter muscle EMG activities following capsaicin application to M2 in M1 CFA-applied rats with Veh (A) or FC (B) injection to TG. C: The mean area under the curve of integrated EMG following capsaicin application to M2 in M1 CFA-applied rats with Veh or FC-injection to TG (C). D and E: Photomicrographs of GFAP-IR cells in TG Veh-injected rats (D) and TG FC-injected rats (E). F: The mean relative number (%) of TG cells encircled with GFAP-IR cells following Veh- (solid bur) or FC- (open bur) administration in M1 CFA rats. G and H: Photomicrographs of pERK-IR cells following M2 capsaicin application in TG Veh- (G) and TG FC-injected rats (H). I: The mean relative number (%) of pERK-IR cells in TG following M2 capsaicin application in TG Veh- and TG FC-injected rats which received CFA in M1. Solid arrow in A indicates the timing of capsaicin application. White arrow heads in D and E indicate GFAP-IR cells and those in G and H are pERK-IR cells, respectively. Veh: vehicle for FC, FC: Fluorocitrate. #: p<0.05, +++: p<0.001, *: p<0.05, **: p<0.01.