Table 2. Demographic and clinical characteristics of participants by cluster based on MLST of Chlamydia trachomatis, STI outpatient clinic, Amsterdam, July 2008–May 2010.
| MSM-associated clusters | Heterosexual-associated clusters | ||||||||||||
| Cluster I(n = 128) | Cluster II(n = 80) | Cluster III(n = 10) | Cluster IV(n = 34) | Cluster V(n = 71) | Cluster VI(n = 77) | Cluster VII(n = 26) | Cluster VIII(n = 25) | Residual Group(n = 75) | ptotal | pI to IV | pV to VIII+R | ||
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||
| ompA genovar | B | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 (3) | – | – | – |
| D | 0 | 80 (100) | 10 (100) | 0 | 10 (14) | 0 | 0 | 0 | 15 (20) | ||||
| E | 0 | 0 | 0 | 0 | 0 | 77 (100) | 26 (100) | 0 | 9 (12) | ||||
| F | 0 | 0 | 0 | 0 | 58 (82) | 0 | 0 | 0 | 3 (4) | ||||
| G | 86 (67) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 16 (21) | ||||
| H | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 (3) | ||||
| I | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 25 (100) | 6 (8) | ||||
| J | 42 (33) | 0 | 0 | 0 | 3 (4) | 0 | 0 | 0 | 11 (15) | ||||
| K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11 (15) | ||||
| L2 | 0 | 0 | 0 | 3 (9) | 0 | 0 | 0 | 0 | 0 | ||||
| L2b | 0 | 0 | 0 | 31 (91) | 0 | 0 | 0 | 0 | 0 | ||||
| Simpson’s diversity index | D (95% CI) | 0.77 (0.72–0.82) | 0. 38 (0. 24–0. 52) | 0.38 (0.03–0.72) | 0.22 (0.04–0.39) | 0.82 (0.74–0.91) | 0.86 (0.81–0.92) | 0.71 (0.53–0.90) | 0.87 (0.80–0.94) | – | – | – | – |
| Sex group | MSMO | 126 (98) | 76 (95) | 9 (90) | 34 (100) | 6 (8) | 10 (13) | 0 | 0 | 1 (1) | <0.001 | 0.062 | 0.022 |
| MSMW | 2 (2) | 1 (1) | 0 | 0 | 3 (4) | 0 | 1 (4) | 0 | 1 (1) | ||||
| MSWO | 0 | 3 (4) | 0 | 0 | 16 (23) | 29 (38) | 7 (27) | 9 (36) | 22 (29) | ||||
| Female | 0 | 0 | 1 (10) | 0 | 46 (65) | 38 (49) | 18 (69) | 16 (64) | 51 (68) | ||||
| Age in years | Median (IQR) | 39 (31–45) | 39 (29–45) | 33 (24–42) | 40 (35–45) | 24 (21–27) | 24 (21–28) | 25 (22–28) | 24 (21–27) | 23 (21–32) | <0.001 | 0.126 | 0.708 |
| Ethnicity a | Dutch | 90 (71) | 57 (71) | 8 (89) | 26 (79) | 49 (69) | 58 (76) | 17 (65) | 12 (48) | 57 (76) | 0.228 | 0.627 | 0.065 |
| Other | 37 (29) | 23 (29) | 1 (11) | 7 (21) | 22 (31) | 18 (24) | 9 (35) | 13 (52) | 18 (24) | ||||
| Residence b | Amsterdam | 99 (79) | 64 (85) | 9 (90) | 24 (75) | 56 (81) | 51 (69) | 18 (69) | 16 (67) | 59 (82) | 0.212 | 0.494 | 0.192 |
| Outside Amsterdam | 27 (21) | 11 (15) | 1 (10) | 8 (25) | 13 (19) | 23 (31) | 8 (31) | 8 (33) | 13 (18) | ||||
| Number of sexual partners in past 6 months c | Median (IQR) | 7 (3–18) | 6 (3–10) | 5 (3–15) | 15 (10–21) | 2 (2–5) | 3 (2–5) | 2 (1–3) | 2 (1–5) | 3 (2–4) | <0.001 | 0.001 | 0.656 |
| Notified for STI | No | 103 (80) | 61 (76) | 9 (90) | 28 (82) | 41 (58) | 58 (75) | 14 (54) | 15 (60) | 55 (73) | 0.005 | 0.782 | 0.059 |
| Yes | 25 (20) | 19 (24) | 1 (10) | 6 (18) | 30 (42) | 19 (25) | 12 (46) | 10 (40) | 20 (27) | ||||
| STI-related complaints | No | 62 (48) | 43 (54) | 3 (30) | 10 (29) | 42 (59) | 36 (47) | 15 (58) | 9 (36) | 32 (43) | 0.085 | 0.073 | 0.149 |
| Yes | 66 (52) | 37 (46) | 7 (70) | 24 (71) | 29 (41) | 41 (53) | 11 (42) | 16 (64) | 43 (57) | ||||
| HIV d | Negative | 73 (59) | 50 (64) | 8 (80) | 4 (13) | 69 (97) | 70 (93) | 25 (100) | 25 (100) | 74 (99) | <0.001 | <0.001 | 0.342 |
| Positive | 50 (41) | 28 (36) | 2 (20) | 28 (88) | 2 (3) | 5 (7) | 0 | 0 | 1 (1) | ||||
| Neisseria gonorrhoeae | Negative | 106 (83) | 66 (83) | 8 (80) | 28 (82) | 63 (89) | 71 (92) | 25 (96) | 19 (76) | 74 (99) | 0.002 | 0.991 | 0.005 |
| Positive | 22 (17) | 14 (18) | 2 (20) | 6 (18) | 8 (11) | 6 (8) | 1 (4) | 6 (24) | 1 (1) | ||||
MLST: multilocus sequence typing; MSM: men who have sex with men; MSMO: men who have sex with men only; MSMW: men who have sex with men and women; MSWO: men who have sex with women only; STI: sexually transmitted infections; IQR: interquartile range.
ptotal represents the p-value for the analyses over all clusters and the residual group; pI to IV over MSM-associated clusters, i.e. clusters I–IV and pV to VIII+R over heterosexual-associated clusters, i.e. clusters V–VIII and the residual group.
Data were missing for 1 sample from cluster I, 1 from cluster III, 1 from cluster IV and 1 from cluster VI.
Data were missing for 2 samples from cluster I, 5 from cluster II, 2 from cluster IV, 2 from cluster V, 3 from cluster VI, 1 from cluster VIII and 3 from the residual group.
Data were missing for 3 samples from cluster I and 3 from cluster II.
Data were missing for 5 samples from cluster I, 2 from cluster II, 2 from cluster IV, 2 from cluster VI and 1 from cluster VII.