Table 3. Clinical and functional characteristics of the IPF patients according to the detection of fibrocytes in BAL.
Fibrocytes(+) | Fibrocytes(−) | P value | |
Number of patients (%) | 14 (54%) | 12 (46%) | |
Age | 73 [56–83] | 75 [65–84] | 0.49 |
Gender (Male) | 12 (85%) | 7 (58%) | 0.12 |
Smoker (ever) | 9 (64%) | 7 (58%) | 1 |
Exacerbation | 1 (7%) | 2 (28%) | 0.58 |
Delay since diagnosis (days) | 13 [0–655] | 17 [0–250] | 0.45 |
Oral steroids | 3 (21%) | 3 (25%) | 1 |
Death or lung transplant | 6 | 4 | 0.7 |
Pulmonary Hypertension (N) | 0 | 3 | 0.08 |
HRCT fibrosis score | 8 [4]–[14] | 8 [6]–[13] | 0.98 |
Fibrocyte count/ml | 5240 [369–29550] | 0 [0–0] | |
CCL2 (pg/ml) | 106 [0–350] | 182 [11–1033] | 0.14 |
CXCL12 (pg/ml) | 0 [0–0] | 0 [0–22.7] | 0.37 |
Lung function tests | |||
VC (% pred) | 79 [34–108] | 70 [40–96] | 0.7 |
DLCO (% pred) | 45 [15–91] | 45 [58–73] | 0.06 |
PaO2 (mm Hg) | 78 [45–101] | 76 [59–92] | 0.48 |
Data are expressed as median [range] or N (%).