Skip to main content
. 2013 Jan 16;8(1):e53736. doi: 10.1371/journal.pone.0053736

Table 4. Clinical and functional characteristics of the IPF patients with positive or negative cultures of fibroblasts.

Fibroblasts (+) Fibroblasts (−) P value
Number of patients (%) 12 (46%) 14 (54%)
Age 75 [66–84] 72 [56–84] 0.4
Gender (Male) 7 (58) 12 (72) 0.06
Smoker (ever) 8 (66) 8 (57) 0.7
Exacerbation 2 1 0.58
Delay since diagnosis (days) 18 [0–236] 7 [0–655] 0.74
Death or lung transplant during follow up 4 (33) 4 (42) 1
Oral steroids 4 (33) 2 (14) 0.36
CCL2 (pg/ml) 269 [102–1033] 64 [0–341] 0.02
CXCL12 (pg/ml) 0 [0–22.7] 0 [0–0] 0.54
PaO2 (mm Hg) 76 [50–101] 77 [45–91] 0.8
VC (% pred) 79 [40–101] 67 [34–108] 0.57
DLCO (% pred) 35 [15–59] 35 [27–91] 0.36
Pulmonary Hypertension 1 2 1
HRCT fibrosis score 8 [4][13] 8 [6][14] 0.56
Detection of Fibrocytes in BAL 5 (41) 9 (64) 0.43

Data are expressed as median [range] or N (%).