Table 4. Genetic association of rs148972953 with risk of having metastasis in MARIE breast cancer cases.

		Wild-type(GG)	Carrier(AG or AA)
Metastasis at	Yes	73	4
baseline	No	2221	69
	p-value	0.276
	OR (95% CI)	1	1.76 (0.62–4.96)
Metastasis after	Yes	203	8
primary treatment	No	2252	66
	p-value	0.435
	OR (95% CI)	1	1.34 (0.63–2.84)

Notes:

The analysis was only performed in breast cancer cases of the MARIE Study. At baseline, 2367 patients suffered from a primary invasive breast cancer and 159 patients suffered from in situ breast cancer; those 159 patients were excluded for this analysis. In the Risk Prediction of Breast Cancer Metastasis Study, information on metastasis was either missing in most patients or the follow-up time was too short for the development of metastasis after primary treatment.

OR … odds ratio.

95% CI … 95% confidence interval.