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. Author manuscript; available in PMC: 2014 Feb 1.
Published in final edited form as: Schizophr Res. 2012 Dec 24;143(2-3):377–383. doi: 10.1016/j.schres.2012.11.023

Figure 3.

Figure 3

MAM treatment induces deficits in auditory information processing in the ventral hippocampus, mediodorsal thalamic nucleus, core of the nucleus accumbens and infralimbic cortex in the left but not right hemisphere. Specifically significant differences are observed in MAM-treated rats in the P50 component of the ventral hippocampus evoked potentials to the conditioning and test stimuli, in the P50 and N100 components of the test response in the mediodorsal thalamic nucleus, in the P50 component of conditioning response in the core of the nucleus accumbens and in both the P50 of the conditioning response and the N100 of the test response in infralimbic cortex. These alterations in the MAM rats are restored to control level following ventral hippocampal stimulation. Left: grand averaged AEPs to the conditioning stimulus. Right: grand averaged AEPs to the test stimulus. The solid bar indicates a significant difference between sham-stimulated SAL and MAM treated animals for the duration of the bar. Arrows indicate the onset of the auditory stimulus.