Fig. 4.
Female C57BL/6 mice have lower brain AMPH levels than males 45 minutes after injection (experiment 5). Levels of AMPH in brain (a) and serum (b) at the time corresponding to maximal behavioral activation after 5 mg/kg AMPH in the single dose and ascending binge paradigms. *Indicates females different from males, ~ ascending different from single dose. n=8–19 per group, total n=56