Table 1. Sociodemographic and Clinical Variables by Bcl-2 Genotype in Each Group.
| Variable differences | AA (n=10) | AG (n=38) | GG (n=32) | Between-group differences | ||||
|---|---|---|---|---|---|---|---|---|
| |
Mean |
SD |
Mean |
SD |
Mean |
SD |
F |
Sig. (2-tailed) |
| Healthy controls (n=40) | ||||||||
| Age (years) | 25.2 | 6.7 | 27 | 4.5 | 26.5 | 6.7 | 0.14 | 0.90a |
| Gender (men/women) | 2/2 | 7/11 | 12/6 | 0.24b | ||||
| Bipolar disorder (n=40) | ||||||||
| Age (years) | 25.8 | 5.8 | 28.5 | 5.8 | 30.7 | 6.8 | 1.4 | 0.24a |
| Gender (men/women) | 2/4 | 9/11 | 3/11 | 0.40b | ||||
| YMRS | 1.6 | 0.5 | 2.5 | 1.7 | 3.10 | 2.3 | 0.6 | 0.5a |
| HDRS | 5.0 | 1.7 | 4.0 | 1.9 | 5.0 | 1.7 | 1.1 | 0.34a |
| Length of illness (years) | 7 | 7.8 | 8.8 | 5.1 | 7.8 | 5.8 | 0.1 | 0.82a |
| Age at first episode (years) | 17.6 | 1.5 | 19.0 | 5 | 21.3 | 3.4 | 1.1 | 0.34a |
| Number of manic episodes | 2.6 | 2.8 | 3.7 | 2.7 | 3.1 | 1.6 | 0.3 | 0.7a |
| Medication use in bipolar disorder | ||||||||
| Lithium | 4/6 | 18/20 | 10/14 | 0.27b | ||||
| Anticonvulsants | 0/6 | 8/20 | 9/14 | 0.03b | ||||
| Antipsychotics | 0/6 | 3/20 | 2/14 | 0.60b | ||||
| Antidepressants | 2/6 | 4/20 | 2/14 | 0.62b | ||||
| Benzodiazepines | 0/6 | 1/20 | 1/14 | 0.79b | ||||
a
ANOVA.
b
χ2 test.
Significance level p<0.05.