Figure 3.
Olanzapine (OLZ) sensitization induced in adolescence and assessed in adulthood. Number of avoidance responses (a) and intertrial crossing (b) made by the rats from the CS-only, OLZ (1.0 mg/kg), OLZ (2.0 mg/kg), and vehicle (VEH) groups on the last training (predrug) day and throughout the five drug test days are expressed as mean+SEM. The same measures on the seventh retraining day and the first OLZ sensitization test day (approximate postnatal days (∼P) 76) are also expressed as mean+SEM and depicted in c and d, respectively. Data from the predrug day and the second OLZ sensitization test day (∼P 92) are depicted in e (avoidance) and f (intertrial crossing), respectively. *p<0.05 relative to the VEH group; #p<0.05 relative to the CS-only group; $p<0.05 relative to the OLZ 1.0 group.