Table 1. Timeline of Events Occurred in Experiment 3 and 4.
Days of study | Approximate age (years) | Manipulation |
---|---|---|
1–2 | PND 31–32 | Habituation to CAR boxes (30 min/day) |
3–12 | PND 33–42 | 10 Days of CAR training (CS–US) |
13–17 | PND 43–47 | 5 Days of drug testing (CS-only) |
18 | PND 48 | 1st PPI test |
19–36 | PND 49–66 | Rest |
37 | PND 67 | 2nd PPI test |
38 | PND 68 | Habituation to CAR boxes (30 min/day) |
39–45 | PND 69–75 | 7 days of CAR retraining (CS–US) |
46 | PND 76 | 1st drug challenge test (CS-only): OLZ 0.50 mg/kg, CLZ 5.0 mg/kg |
47 | PND 77 | 3rd PPI test |
48–59 | PND 78–89 | Rest |
60 | PND 90 | 1st retraining (CS-only) |
61 | PND 91 | 2nd retraining (CS–US) |
62 | PND 92 | 2nd drug challenge test (CS-only): OLZ 0.50 mg/kg, CLZ 5.0 mg/kg |
The bold text highlight the critical steps of the experiments.