Table 2.
Parameters | Groups | p value | |
---|---|---|---|
NACT (n=29) | NACT+rh-endostatin (n=28) | ||
Ktrans (min -1 ) | |||
Pre-treatment | 0.51 ± 0.16 | 0.57 ± 0.18 | 0.891 |
Post-treatment | 0.25 ± 0.12 | 0.20 ± 0.08 | 0.032 |
Changes | 0.26 ± 0.07 | 0.37 ± 0.11 | 0.026 |
ve | |||
Pre-treatment | 0.74 ± 0.18 | 0.71 ± 0.24 | 0.935 |
Post-treatment | 0.46 ± 0.16 | 0.34 ± 0.15 | 0.021 |
Changes | 0.28 ± 0.09 | 0.37 ± 0.12 | 0.023 |
SER (% ) | |||
Pre-treatment | 216.28 ± 83.56 | 237.28 ± 78.56 | 0.827 |
Post-treatment | 112.75 ± 36.35 | 85.28 ± 21.94 | 0.042 |
Changes | 103.93 ± 24.18 | 152.61 ± 28.37 | 0.018 |
MVD | |||
Post-treatment | 36.05 ± 9.64 | 18.67±6.53 | 0.000 |
Ki-67 proliferation index (%) | |||
Post-treatment | 32.79 ± 10.25% | 12.47 ± 5.11% | 0.000 |