Table 1.
Correlation between expression TFF1 and TFF3 and clinicopathological parameters.
| Variables | No. of cases |
TFF1 expression | p value* | TFF3 expression | p value* | |||
|---|---|---|---|---|---|---|---|---|
| preserved | reduced | low | high | |||||
| Age (yr) | < 60 | 158 | 78(49.4) | 80(50.6) | 0.243 | 89(56.3) | 69(43.7) | 0.850 |
| ≥60 | 134 | 57(42.5) | 77(57.5) | 74(55.2) | 60(44.8) | |||
| Sex | male | 186 | 81(43.5) | 105(56.5) | 0.223 | 105(56.5) | 81(43.5) | 0.774 |
| female | 106 | 54(50.9) | 52(49.1) | 58(54.7) | 48(45.3) | |||
| Histologic type | differentiated | 169 | 61(36.1) | 108(63.9) | 0.000 | 106(62.7) | 63(37.3) | 0.005 |
| undifferentiated | 123 | 74(60.2) | 49(39.8) | 57(46.3) | 66(53.7) | |||
| Lauren classification | intestinal | 193 | 68(35.2) | 125(64.8) | 0.000 | 121(62.7) | 72(37.3) | 0.001 |
| diffuse | 99 | 67(67.7) | 32(32.3) | 42(42.4) | 57(57.6) | |||
| Depth of invasion | T1 | 125 | 53(42.4) | 72(57.6) | 0.256 | 77(61.6) | 48(38.4) | 0.085 |
| T2-4 | 167 | 82(49.1) | 85(50.9) | 86(51.5) | 81(48.5) | |||
| Lymph node metastasis | Absent | 153 | 67(43.8) | 86(56.2) | 0.380 | 103(67.3) | 50(32.7) | 0.000 |
| present | 139 | 68(48.9) | 71(51.1) | 60(43.2) | 79(56.8) | |||
| Lymphatic invasion | Absent | 140 | 67(47.9) | 73(52.1) | 0.593 | 90(64.3) | 50(35.7) | 0.005 |
| Present | 152 | 68(44.7) | 84(55.3) | 73(48.0) | 79(52.0) | |||
| Vein invasion | Absent | 257 | 119(46.3) | 138(53.7) | 0.948 | 150(58.4) | 107(41.6) | 0.018 |
| Present | 35 | 16(45.7) | 19(54.3) | 13(37.1) | 22(62.9) | |||
| Perineural invasion | Absent | 191 | 81(42.4) | 110(57.6) | 0.071 | 110(57.6) | 81(42.4) | 0.402 |
| present | 101 | 54(53.5) | 47(46.5) | 53(52.5) | 48(47.5) | |||
| p-Stage | I | 134 | 56(58.2) | 78(58.2) | 0.161 | 88(65.7) | 46(34.3) | 0.002 |
| II-III | 158 | 79(50.0) | 79(50.0) | 75(47.5) | 83(52.5) | |||
Values are presented as number (%). p-Stage, pathologic stage. * p < 0.05.