Table 2.
Variables | GC (n=292) | EGC (n=125) | AGC (n=167) | ||||
---|---|---|---|---|---|---|---|
n | p value* | n | p value* | n | p value* | ||
Age (yr) | < 60 | 158 | 0.137 | 70 | 0.091 | 88 | 0.484 |
≥60 | 134 | 55 | 79 | ||||
Sex | male | 186 | 0.554 | 77 | 0.359 | 109 | 0.266 |
female | 106 | 48 | 58 | ||||
Histologic type | differentiated | 169 | 0.905 | 81 | 0.476 | 88 | 0.771 |
undifferentiated | 123 | 44 | 79 | ||||
Lauren classification | intestinal | 193 | 0.750 | 92 | 0.168 | 101 | 0.590 |
diffuse | 99 | 33 | 66 | ||||
Depth of invasion | T1 | 125 | 0.000 | ||||
T2-4 | 167 | ||||||
Lymph node metastasis | Absent | 153 | 0.000 | 84 | 0.004 | 69 | 0.000 |
present | 139 | 41 | 98 | ||||
Lymphatic invasion | Absent | 140 | 0.000 | 85 | 0.009 | 55 | 0.000 |
Present | 152 | 40 | 112 | ||||
Vein invasion | Absent | 257 | 0.010 | 120 | 0.931 | 137 | 0.000 |
Present | 35 | 5 | 30 | ||||
Perineural invasion | Absent | 191 | 0.000 | 118 | 1.555 | 73 | 0.000 |
present | 101 | 7 | 94 | ||||
p-Stage | I | 134 | 0.000 | 107 | 0.000 | 27 | 0.003 |
II-III | 158 | 18 | 140 | ||||
TFF1 expression | preserved | 135 | 0.797 | 53 | 0.271 | 82 | 0.473 |
reduced | 157 | 72 | 85 | ||||
TFF3 expression | low | 163 | 0.058 | 77 | 0.048 | 86 | 0.524 |
high | 129 | 48 | 81 | ||||
TFF1/TFF3 expression | reduced/high | 50 | 0.692 | 20 | 0.004 | 30 | 0.175 |
others | 242 | 105 | 137 |
GC, gastric cancer; EGC, early gastric cancer; AGC, advanced gastric cancer. p-Stage, pathologic stage. * p < 0.05.