Figure 3.

ZMPSTE24 transcript levels increase after broadband light (BBL) treatment. (a) Schematic of ZMPSTE24 locus on chromosome 1, hg18. The 3′-seq (deep sequencing of RNA 3′ end) reads were plotted for two old individuals with and without BBL treatment and two untreated young samples. (b) ZMPSTE24 transcript expression is lower in untreated old skin compared with untreated young skin by quantitative reverse transcription–PCR (RT–qPCR). ZMPSTE24 transcript expression in untreated middle-aged skin is intermediate (n=1).