Figure 1. Dissociated mouse rod perikarya express voltage-operated Ca2+ channels.
Cell preparation dissociated from transgenic Nrl:GFP (A) and mOPS driven mCherry- (B) expressing retinas shows a fluorescently tagged population corresponding to rod photoreceptors. Scale bars, 20 μm. C, soma diameter size analysis of GFP and mCherry-expressing rods shows significant overlap with rods dissociated from wild type retinas. D, depolarization-evoked [Ca2+]i increases in rods are antagonized by the L-type channel inhibitor nicardipine (P < 0.001).