. Author manuscript; available in PMC: 2013 Jan 17.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2006 Aug;15(8):1443–1450. doi: 10.1158/1055-9965.EPI-06-0144

Table 3.

Number and type of Ki-ras mutation, effected codon, and amino acid change

Codon	Type of mutation^*	No. of mutations (%)	Wild-type codon (amino acids)	Mutated codon (amino acids)^†	Altered amino acids
12 (n = 112)	G-to-T	57 (41.3%)	GGT (Gly)	GTT (Val)	45 (32.6)
				TGT (Cys)	12 (8.7)
	G-to-A	44 (31.9)		GAT (Asp)	32 (23.2)
				AGT (Ser)	12 (8.7)
	G-to-C	10 (7.2)		GCT (Ala)	8 (5.8)
				CGT (Arg)	2 (1.4)
	T-to-C	1 (0.7)		GGC (Gly)	No change
13 (n = 26)	G-to-T	2 (1.4)	GGC (Gly)	TGC (Arg)	2 (1.4)
	G-to-A	23 (16.7)		GAC (Asp)	22 (15.9)
				GAC (Asp)	1 (0.7)
	G-to-C	1 (0.7)		AGC (Ser)	1 (0.7)

For seven subjects, two mutations were found and are included.

^†

Amino acids abbreviated as follows: glycine (Gly), valine (Val), cysteine (cys), aspartic acid (Asp), alanine (Ala), arginine (Arg), and serine (Ser).