Table 1.
Reference interval of liver function tests in north Indian population
| Total bilirubin | Direct bilirubin | SGOT | SGPT | ALP | GGT | Protein | Albumin | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Total | Median | 0.70 | 0.30 | 25.00 | 25.00 | 200.00 | 16.00 | 7.30 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.0 | 10.0 | 107.0 | 5.0 | 6.40 | 3.50 | |
| 97.5 | 1.30 | 0.50 | 52.80 | 68.0 | 361.8 | 50.60 | 8.30 | 4.90 | ||
| 90 % CI | Lower | 0.18–0.42 | 0.06–0.14 | 12.47–13.53 | 9.24–10.76 | 103.28–110.72 | 4.33–5.67 | 6.38–6.42 | 3.36–3.64 | |
| Upper | 1.18–1.42 | 0.46–0.54 | 52.27–53.33 | 67.24–68.76 | 358.08–365.52 | 49.93–51.27 | 8.28–8.32 | 4.86–4.94 | ||
| Male | Median | 0.70 | 0.30 | 26.00 | 28.00 | 210.00 | 17.00 | 7.30 | 4.20 | |
| 95 Percentile | 2.5 | 0.40 | 0.10 | 14.00 | 11.00 | 116.30 | 6.76 | 6.37 | 3.60 | |
| 97.5 | 1.34 | 0.50 | 55.00 | 70.35 | 388.00 | 51.09 | 8.30 | 4.80 | ||
| 90 % CI | Lower | 0.22–0.58 | 0.02–0.18 | 13.29–14.71 | 9.94–12.06 | 111.01–121.59 | 5.80–7.72 | 6.33–6.41 | 3.58–3.62 | |
| Upper | 1.16–1.52 | 0.42–0.58 | 54.29–55.71 | 69.29–71.41 | 382.71–393.29 | 50.13–52.05 | 8.26–8.34 | 4.78–4.82 | ||
| Female | Median | 0.60 | 0.30 | 24.00 | 22.00 | 192.00 | 14.00 | 7.40 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 9.00 | 100.58 | 3.92 | 6.50 | 3.40 | |
| 97.5 | 1.20 | 0.50 | 50.43 | 63.43 | 323.00 | 48.70 | 8.30 | 4.60 | ||
| 90 % CI | Lower | 0.12–0.48 | 0.02–0.18 | 12.22–13.78 | 7.92–10.08 | 95.60–105.56 | 3.08–4.76 | 6.46–6.54 | 3.38–3.42 | |
| Upper | 1.02–1.38 | 0.42–0.58 | 49.65–51.21 | 62.35–64.51 | 318.02–327.98 | 47.86–49.54 | 8.26–8.34 | 4.58–4.62 | ||
| Age <20 years | Median | 0.70 | 0.30 | 26.00 | 22.00 | 261.00 | 13.00 | 7.50 | 4.30 | |
| 95 Percentile | 2.5 | 0.40 | 0.10 | 15.00 | 12.00 | 118.00 | 2.30 | 6.50 | 3.80 | |
| 97.5 | 1.50 | 0.50 | 50.00 | 56.00 | 622.00 | 48.43 | 8.20 | 4.70 | ||
| 90 % CI | Lower | 0.34–0.46 | 0.08–0.12 | 13.43–16.57 | 9.92–14.08 | 93.48–142.52 | 0.18–4.42 | 6.42–6.58 | 3.76–3.84 | |
| Upper | 1.44–1.56 | 0.48–0.52 | 48.43–51.57 | 53.92–58.08 | 597.48–646.52 | 49.88–54.12 | 8.16–8.24 | 4.66–4.74 | ||
| Age 20–40 years | Median | 0.70 | 0.30 | 25.00 | 25.00 | 196.00 | 16.00 | 7.40 | 4.20 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 9.50 | 103.58 | 6.00 | 6.40 | 3.5 | |
| 97.5 | 1.30 | 0.50 | 52.00 | 71.00 | 328.00 | 52.00 | 8.30 | 4.70 | ||
| 90 % CI | Lower | 0.12-0.48 | 0.02–0.18 | 12.29–13.71 | 8.38–10.62 | 99.01–108.15 | 5.31–6.69 | 6.36–6.44 | 3.48–3.52 | |
| Upper | 1.12–1.48 | 0.42–0.58 | 51.29–52.71 | 69.88–72.12 | 323.43–332.57 | 47.74–49.12 | 8.26–8.34 | 4.68–4.72 | ||
| Age 41–60 years | Median | 0.60 | 0.30 | 26.00 | 25.00 | 202.00 | 17.00 | 7.20 | 4.10 | |
| 95 Percentile | 2.5 | 0.35 | 0.10 | 13.00 | 10.20 | 114.20 | 5.00 | 6.40 | 3.50 | |
| 97.5 | 1.20 | 0.50 | 54.80 | 65.00 | 318.00 | 54.00 | 8.30 | 4.70 | ||
| 90 % CI | Lower | 0.33–0.37 | 0.02–0.18 | 12.10–13.90 | 8.98–11.42 | 109.81–118.59 | 3.61–6.39 | 6.36–6.44 | 3.50–3.54 | |
| Upper | 1.18–1.22 | 0.42–0.58 | 53.90–55.70 | 63.78–66.22 | 313.61–322.39 | 52.61–55.39 | 8.26–8.34 | 4.68–4.72 | ||
| Rural | Median | 0.70 | 0.30 | 26.00 | 23.00 | 197.00 | 14.00 | 7.30 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 9.34 | 102.18 | 3.84 | 6.50 | 3.40 | |
| 97.5 | 1.20 | 0.50 | 50.00 | 63.00 | 430.25 | 43.48 | 8.10 | 4.70 | ||
| 90 % CI | Lower | 0.28–0.32 | 0.02–0.18 | 12.12–13.88 | 8.24–10.44 | 95.48–108.88 | 2.57–5.11 | 6.46–6.54 | 3.38–3.42 | |
| Upper | 1.18–1.22 | 0.42–0.58 | 49.12–50.88 | 61.90–64.10 | 423.55–436.95 | 42.21–44.75 | 8.06–8.14 | 4.68–4.72 | ||
| Urban | Median | 0.62 | 0.30 | 25.00 | 26.00 | 205.00 | 17.00 | 7.30 | 4.20 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.53 | 10.00 | 111.05 | 6.00 | 6.40 | 3.60 | |
| 97.5 | 1.30 | 0.50 | 55.00 | 71.00 | 344.00 | 52.00 | 8.40 | 4.70 | ||
| 90 % CI | Lower | 0.14–0.46 | 0.04–0.16 | 12.86–14.20 | 8.96–11.04 | 106.09–116.01 | 5.27–6.73 | 6.36–6.44 | 3.40–3.80 | |
| Upper | 1.14–1.46 | 0.44–0.56 | 54.33–55.67 | 69.96–72.04 | 339.57–348.43 | 51.27–52.73 | 8.36–8.44 | 4.50–4.90 | ||
| BMI < 25 | Median | 0.70 | 0.30 | 25.00 | 24.00 | 199.00 | 15.00 | 7.30 | 4.20 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 10.00 | 104.63 | 5.00 | 6.40 | 3.50 | |
| 97.5 | 1.30 | 0.50 | 52.00 | 66.00 | 388.00 | 50.23 | 8.30 | 4.70 | ||
| 90 % CI | Lower | 0.14–0.46 | 0.04–0.16 | 12.41–13.59 | 9.18–10.82 | 100.30–108.96 | 4.24–5.76 | 6.38–6.42 | 3.32–3.68 | |
| Upper | 1.14–1.46 | 0.44–0.56 | 51.41–52.59 | 65.18–66.82 | 383.67–392.33 | 49.47–50.99 | 8.28–8.32 | 4.52–4.88 | ||
| BMI ≥ 25 | Median | 0.60 | 0.30 | 25.00 | 28.00 | 200.00 | 18.00 | 7.20 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.80 | 10.00 | 117.90 | 7.00 | 6.36 | 3.60 | |
| 97.5 | 1.30 | 0.50 | 55.40 | 79.00 | 310.60 | 62.36 | 8.24 | 4.60 | ||
| 90 % CI | Lower | 0.28–0.32 | 0.00–0.20 | 12.57–15.03 | 8.06–11.94 | 111.12–124.68 | 5.69–8.31 | 6.30–6.42 | 3.56–3.64 | |
| Upper | 1.14–1.46 | 0.40–0.60 | 54.17–56.63 | 77.06–80.94 | 303.82–317.38 | 61.63–63.09 | 8.18–8.30 | 4.56–4.64 | ||
| Vegetarian | Median | 0.67 | 0.30 | 24.00 | 24.00 | 198.00 | 15.00 | 7.30 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 9.50 | 104.00 | 5.00 | 6.44 | 3.50 | |
| 97.5 | 1.30 | 0.50 | 52.58 | 68.00 | 417.75 | 49.15 | 8.30 | 4.90 | ||
| 90 % CI | Lower | 0.14–0.46 | 0.04–0.16 | 12.37–13.63 | 8.60–10.40 | 99.37–108.63 | 4.18–5.82 | 6.42–6.46 | 3.32–3.68 | |
| Upper | 1.14–1.46 | 0.44–0.56 | 51.95–53.21 | 67.10–68.90 | 413.12–422.38 | 48.33–49.97 | 8.28–8.32 | 4.70–5.10 | ||
| Non Vegetarian | Median | 0.70 | 0.30 | 26.00 | 27.00 | 212.00 | 18.00 | 7.30 | 4.20 | |
| 95 Percentile | 2.5 | 0.40 | 0.10 | 13.40 | 10.00 | 112.40 | 7.50 | 6.28 | 3.60 | |
| 97.5 | 1.30 | 0.50 | 53.20 | 67.50 | 344.20 | 52.18 | 8.40 | 4.80 | ||
| 90 % CI | Lower | 0.38–0.42 | 0.00–0.20 | 12.46–14.34 | 8.53–11.47 | 106.36–118.44 | 6.40–8.60 | 6.22–6.34 | 3.58–3.62 | |
| Upper | 1.28–1.32 | 0.40–0.60 | 52.26–54.14 | 66.03–68.97 | 338.16–350.24 | 51.08–53.28 | 8.34–8.46 | 4.78–4.82 | ||
| Smokers | Median | 0.70 | 0.30 | 28.00 | 32.00 | 204.50 | 21.00 | 7.20 | 4.10 | |
| 95 Percentile | 2.5 | 0.40 | 0.10 | 14.00 | 12.00 | 98.00 | 8.80 | 6.40 | 3.60 | |
| 97.5 | 1.20 | 0.50 | 60.00 | 66.00 | 323.00 | 58.00 | 8.40 | 4.80 | ||
| 90 % CI | Lower | 0.36–0.44 | 0.02–0.22 | 12.47–15.53 | 10.26–13.74 | 90.77–105.23 | 7.15–10.45 | 6.34–6.46 | 3.56–3.64 | |
| Upper | 1.16–1.24 | 0.38–0.62 | 59.06–60.94 | 64.53–67.47 | 315.77–330.23 | 56.35–59.65 | 8.34–8.46 | 4.76–4.84 | ||
| Alcoholic | Median | 0.70 | 0.30 | 29.00 | 33.00 | 206.00 | 24.00 | 7.20 | 4.10 | |
| 95 Percentile | 2.5 | 0.39 | 0.20 | 14.00 | 11.00 | 98.85 | 9.00 | 6.39 | 3.60 | |
| 97.5 | 1.30 | 0.50 | 60.00 | 84.00 | 324.65 | 75.80 | 8.23 | 4.80 | ||
| 90 % CI | Lower | 0.37–0.41 | 0.10–0.30 | 12.65–15.35 | 9.45–12.55 | 92.60–105.10 | 7.16–10.84 | 6.33–6.45 | 3.56–3.64 | |
| Upper | 1.28–1.32 | 0.38–0.62 | 59.06–60.94 | 66.53–69.47 | 318.40–330.90 | 64.70–66.90 | 8.17–8.29 | 4.76–4.84 | ||
| Pre Menopause | Median | 0.60 | 0.30 | 24.00 | 20.00 | 180.00 | 13.00 | 7.40 | 4.10 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 9.00 | 98.00 | 3.80 | 6.50 | 3.40 | |
| 97.5 | 1.20 | 0.50 | 50.35 | 61.35 | 423.75 | 40.70 | 8.22 | 4.70 | ||
| 90 % CI | Lower | 0.28–0.32 | 0.00–0.20 | 11.94–14.06 | 7.67–10.33 | 90.89–105.11 | 2.80–4.80 | 6.46–6.54 | 3.36–3.44 | |
| Upper | 1.18–1.22 | 0.40–0.60 | 49.29–51.41 | 60.02–62.68 | 416.64–430.86 | 39.70–41.70 | 8.18–8.26 | 4.66–4.74 | ||
| Post Menopause | Median | 0.60 | 0.30 | 25.00 | 24.00 | 208.50 | 15.10 | 7.30 | 4.00 | |
| 95 Percentile | 2.5 | 0.30 | 0.10 | 13.00 | 8.00 | 115.78 | 5.00 | 6.48 | 3.58 | |
| 97.5 | 1.20 | 0.50 | 51.23 | 66.45 | 314.00 | 52.20 | 8.32 | 4.60 | ||
| 90 % CI | Lower | 0.28–0.32 | 0.00–0.22 | 11.84–14.16 | 6.24–9.76 | 109.47–122.09 | 3.59–6.41 | 6.42–6.54 | 3.54–3.62 | |
| Upper | 1.18–1.22 | 0.38–0.62 | 50.07–52.39 | 64.69–68.21 | 307.69–320.31 | 50.79–53.61 | 8.26–8.38 | 4.56–4.64 | ||