Figure 6.

Repeated social defeat leads to slower sIPSC kinetics in lwDR 5-HT neurons. (A) Raw data traces from representative lwDR recordings. The inset (Aiii) demonstrates the averaged event from the respective traces in Ai and Aii. Scale bar is 20 pA, 512 ms. Note the differences in the shape, i.e., kinetics, of the two averaged events. (B) Comparison of the mean values of each treatment group demonstrate a slower decay time 50% and consequent increase in charge transfer in neurons recorded from intruders while the frequency, rise time, and amplitude remain comparable to controls. Error bars indicate mean ± SEM; *p < 0.05 Student’s t test.