Barrel cortex in VMAT2sert-cre mice. (A,B) Coronal sections stained with Nissl from P7 control
(A) and recombined (B) littermates. This shows the lack of cytoarchitectural
defects in the cerebral cortex and hippocampus; a minor reduction
in thickness of upper cortical layers exists in the recombined. (C,D)
Flattened cortex of P10 control and VMAT2sert-cre sectioned through the somatosensory cortex and stained for SERT
immunohistochemistry (C,D) showed well clustered thalamo-cortical
afferents. Nissl staining (E,F) and Cux1 labeling (G,H) outlined the
barrel walls in layer IV, similarly to observations in controls.