Table 1.
Literature Curated Interactions. List of Interactions Found for the HPV E2 Proteins in the VirHostNet, virusMINT and PubMed Databases
| ENSembl ID | Official Gene Symbol | Name | Synonyms | HPV Type | Refs. |
|---|---|---|---|---|---|
| ENSG00000065000 | AP3D1 | adaptor-related protein complex 3, delta 1 subunit | ADTD | HPV16 | [123] |
| ENSG00000012048 | BRCA1 | breast cancer 1, early onset | BRCC1, PPP1R53, RNF53 | HPV18 | [124] |
| ENSG00000141867 | BRD4 | bromodomain containing 4 | CAP, HUNK1, HUNKI, MCAP | HPV16,18,31,11,6,8,1 | [55, 125, 126] |
| ENSG00000064726 | BTBD1 | BTB (POZ) domain containing 1 | HPV16 | [90] | |
| ENSG00000133243 | BTBD2 | BTB (POZ) domain containing 2 | HPV16 | [90] | |
| ENSG00000108561 | C1QBP | complement component 1, q subcomponent binding protein | gC1Q-R, gC1qR, HABP1, p32, SF2p32 | HPV5 | [60] |
| ENSG00000064012 | CASP8 | caspase 8, apoptosis-related cysteine peptidase | Casp-8, FLICE, MACH, MCH5 | HPV16,18 | [66] |
| ENSG00000206355 | CCHCR1 | coiled-coil alpha-helical rod protein 1 | C6orf18, HCR | HPV16 | [90] |
| ENSG00000117399 | CDC20 | cell division cycle 20 homolog | CDC20A, p55CDC | HPV16,18 | [7] |
| ENSG00000245848 | CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | C/EBP-alpha, CEBP | HPV16,18,8 | [103] |
| ENSG00000172216 | CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5 | HPV16,18,8 | [103] |
| ENSG00000003402 | CFLAR | CASP8 and FADD-like apoptosis regulator | c-FLIP, CASH, CASP8AP1, Casper, CLARP, FLAME, FLIP, I-FLICE, MRIT | HPV16 | [68] |
| ENSG00000160917 | CPSF4 | cleavage and polyadenylation specific factor 4 | CPSF30, NAR | HPV16 | [62] |
| ENSG00000005339 | CREBBP | CREB binding protein | CBP, KAT3A, RSTS, RTS | HPV18 | [31] |
| ENSG00000036257 | CUL3 | cullin 3 | HPV16 | [88] | |
| ENSG00000013573 | DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 | CHL1, CHLR1, KRG2 | HPV16,11 | [56] |
| ENSG00000242372 | EIF6 | eukaryotic translation initiation factor 6 | b(2)gcn, EIF3A, ITGB4BP, p27BBP | HPV16 | [123] |
| ENSG00000100393 | EP300 | E1A binding protein p300 | KAT3B, p300 | HPV18,5,8 | [32] |
| ENSG00000183495 | EP400 | E1A binding protein p400 | CAGH32, DKFZP434I225, KIAA1498, KIAA1818, P400, TNRC12 | HPV16 | [23] |
| ENSG00000105325 | FZR1 | fizzy/cell division cycle 20 related 1 | CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, KIAA1242 | HPV16,18 | [7] |
| ENSG00000204628 | GNB2L1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | Gnb2-rs1, H12.3, RACK1 | HPV16 | [123] |
| ENSG00000132522 | GPS2 | G protein pathway suppressor 2 | HPV16 | [127] | |
| ENSG00000137947 | GTF2B | general transcription factor IIB | TFIIB | HPV16 | [128] |
| ENSG00000180806 | HoxC9 | homeobox C9 | HOX3, HOX3B | HPV16 | [90] |
| ENSG00000114166 | KAT2B | K(lysine) acetyltransferase 2B | GCN5, GCN5L, P/CAF, PCAF | HPV16,18,11,6 | [30] |
| ENSG00000126012 | KDM5C | lysine (K)-specific demethylase 5C | DXS1272E, JARID1C, SMCX, XE169 | HPV16 | [23] |
| ENSG00000112984 | KIF20A | kinesin family member 20A | RAB6KIFL | HPV16,11 | [57] |
| ENSG00000135679 | MDM2 | Mdm2 p53 binding protein homolog | HDM2, HDMX, MGC5370 | HPV16 | [129] |
| ENSG00000187109 | NAP1L1 | nucleosome assembly protein 1-like 1 | MGC23410, MGC8688, NAP1, NAP1L, NRP | HPV18,5,8 | [34] |
| ENSG00000123358 | NR4A1 | nuclear receptor subfamily 4, group A, member 1 | GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3 | HPV16 | [70] |
| ENSG00000104904 | OAZ1 | ornithine decarboxylase antizyme 1 | AZI, MGC138338, OAZ | HPV16 | [123] |
| ENSG00000143799 | PARP1 | poly (ADP-ribose) polymerase 1 | ADPRT, PARP, PPOL | HPV18 | [130] |
| ENSG00000166851 | PLK1 | polo-like kinase 1 | PLK | HPV5 | [131] |
| ENSG00000132963 | POMP | proteasome maturation protein | C13orf12, HSPC014, UMP1 | HPV16 | [123] |
| ENSG00000214517 | PPME1 | protein phosphatase methylesterase 1 | PME-1 | HPV16 | [123] |
| ENSG00000168066 | SF1 | splicing factor 1 | ZFM1, ZNF162 | HPV16 | [90] |
| ENSG00000136450 | SFRS1 | serine/arginine-rich splicing factor 1 | ASF, MGC5228, SF2, SF2p33, SFRS1, SRp30a | HPV5 | [60] |
| ENSG00000161547 | SFRS2 | serine/arginine-rich splicing factor 2 | PR264, SC-35, SC35, SFRS2, SFRS2A | HPV5 | [60] |
| ENSG00000115875 | SFRS7 | serine/arginine-rich splicing factor 7 | 9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2 | HPV5 | [60] |
| ENSG00000145604 | SKP2 | S-phase kinase-associated protein 2 (p45) | FBL1, FBXL1 | HPV18 | [85] |
| ENSG00000099956 | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | BAF47, hSNFS, Ini1, RDT, Sfh1p, SNF5L1, Snr1 | HPV18 | [33] |
| ENSG00000172062 | SMN1 | survival of motor neuron 1, telomeric | BCD541, SMA, SMA1, SMA2, SMA3, SMA@, SMNT | HPV16,18,11 | [64] |
| ENSG00000104852 | SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | RNPU1Z, RPU1, Snp1, SNRP70, U1-70K | HPV5 | [58] |
| ENSG00000185591 | SP1 | Sp1 transcription factor | HPV18,8 | [39. 132] | |
| ENSG00000147133 | TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, NSCL2, TAF2A, TAFII250 | HPV16,18 | [133] |
| ENSG00000106290 | TAF6 | TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa | MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85 | HPV18 | [134] |
| ENSG00000178913 | TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | TAF2F, TAFII55 | HPV5 | [135] |
| ENSG00000106052 | TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | CALCOCO3, TXBP151 | HPV16,18 | [91] |
| ENSG00000112592 | TBP | TATA box binding protein | GTF2D1, SCA17, TFIID | HPV16,8 | [135] |
| ENSG00000144747 | TMF1 | TATA element modulatory factor 1 | ARA160, TMF | HPV16 | [90] |
| ENSG00000064419 | TNPO3 | transportin 3 | IPO12, MTR10A, TRN-SR, TRN-SR2 | HPV5 | [60] |
| ENSG00000198900 | TOP1 | topoisomerase (DNA) I | HPV16 | [78] | |
| ENSG00000163781 | TOPBP1 | topoisomerase (DNA) II binding protein 1 | KIAA0259, TOP2BP1 | HPV16 | [136] |
| ENSG00000141510 | TP53 | tumor protein p53 | LFS1, p53 | HPV16,18 | [9,137] |
| ENSG00000136527 | TRA2B | transformer 2 beta homolog | Htra2-beta, SFRS10 | HPV5 | [60] |
| ENSG00000082512 | TRAF5 | TNF receptor-associated factor 5 | RNF84 | HPV1,3,5,6,8,9,11,16,18,33,39 | [5] |
| ENSG00000175104 | TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase | RNF85 | HPV1,3,5,6,8,9,11,16,18,33,39 | [5] |