Table 3.
Comparison of genotypic variations of the TYMS among individuals with BC and controls
|
Genotypic variant of the TYMS |
|||
|---|---|---|---|
| 2R/2R | 2R/3R | 3R/3R | |
|
SBC |
04 |
22 |
05 |
|
Control |
36 |
49 |
47 |
|
χ2 |
2.80 |
10.4 |
3.53 |
|
p |
0.11 |
0.001 |
0.06 |
|
OR |
0.30 |
4.14 |
0.35 |
|
CI (95%) |
(0.13-1.21) |
(1.77-9.71) |
(0.12-0.97) |
|
HBC |
03 |
25 |
09 |
|
Control |
36 |
49 |
47 |
|
χ2 |
5.94 |
9.68 |
1.9 |
|
p |
0.01 |
0.002 |
0.27 |
|
OR |
0.23 |
3.53 |
0.58 |
|
CI (95%) |
(0.06-0.81) |
(1.63-7.65) |
(0.25-1.33) |
|
BC |
07 |
47 |
14 |
|
Control |
36 |
49 |
47 |
|
χ2 |
2.46 |
17.13 |
0.39 |
|
p |
0.12 |
<0.001 |
0.53 |
|
OR |
0.45 |
3.79 |
0.47 |
| CI (95%) | (0.19-1.11) | (2.03-7.08) | (0.24-1.52) |
χ2 = Chi-square; OR = Odds Ratio; CI = Confidence Interval; In Bold = Significant Statistical Values; SBC = sporadic breast cancer; HBC = hereditary breast cancer; BC = breast cancer.