Table 3.
Functional classification of the proteins selected after ICPL™
| Over represented in DF pool | Over represented in SD pool | Functional category | Subcellular location | Comments |
|---|---|---|---|---|
| Peroxiredoxin 2 |
- |
Oxidative stress regulatory protein |
Cytosol |
Interacts with G3BP |
|
- |
Galectin-3 Binding Protein (G3BP) |
cell-cell and cell-matrix interactions; immune response (natural killer and cytotoxicity) |
Secreted |
Interacts with Peroxiredoxin 2 |
|
- |
Vitamin D Binding-Protein |
Multifunctional; Vitamin D transportation (albumin protein familly) |
Secreted |
- |
|
- |
Afamin |
Multifunctional; Vitamin E transportation (albumin protein family) |
Secreted |
- |
|
- |
Fibronectin |
Cell migration, adhesion and matrix organization |
Secreted |
Interacts with LRG1 |
|
- |
Leucine-Rich Glycoprotein 1(LRG1) |
protein-protein interaction, signal transduction, and cell adhesion and development |
Secreted |
Interacts with Fibronectin |
|
- |
C-Reactive Protein |
Response to inflammation |
Secreted |
- |
| - | Ferritin LC | Iron storage and release | Cytosol | - |