Table 4.
Distribution of STAT6 and IL10RA haplotypes
| Gene ID | Haplotypes | Unc. Malaria n=358(%) | Asymptomatic n=276(%) | OR (95%CI) | P value |
|---|---|---|---|---|---|
|
STAT6(rs3024941/ rs3024943 /rs3024944) |
CGG |
276 (0.771) |
193 (0.699) |
1.4 (1.0-2.0) |
0.054 |
| GAG |
43 (0.121 |
36 (0.130) |
NA |
NS |
|
| CGC |
38 (0.106) |
43 (0.156) |
NA |
NS |
|
| CAG |
1 (0.002) |
0 (0) |
NA |
NS |
|
| GAC |
0 (0) |
3 (0.011) |
NA |
NS |
|
| CAC |
0 (0) |
1 (0.004) |
NA |
NS |
|
| IL10RA(rs56356146 /rs7925112 /ss491228441) | CTT |
284 (0.8) |
209 (0.758) |
NA |
NS |
| TTT |
44 (0.12) |
40 (0.145) |
NA |
NS |
|
| CCT |
26 (0.07) |
14 (0.05) |
NA |
NS |
|
| CTG |
3 (0.008) |
13 (0.047) |
0.16 (0.04-0.61) |
0.007 |
|
| TCT | 1 (0.002) | 0 (0) | NA | NS |
NA: not applicable; NS: not significant; Unc malar: uncomplicated malaria; Asym: asymptomatic, Odds ratio and P value were calculated by using binary logistic regression model and adjusted for age and gender.