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. 2013 Jan 17;9(1):e1002859. doi: 10.1371/journal.pcbi.1002859

Figure 5. Results of gene expression analysis and flux measurements on DNL pathway.

Figure 5

Circles represent the corresponding metabolites, and arrows represent reactions. ELOVL6 and SCD1 are the genes that express enzymes, which catalyze the corresponding reactions. This independent wet-lab study shows that (i) flux through Decanoic Acid to Stearic is decreased, and (ii) the shown genes that catalyze corresponding reactions are down-regulated in 3-week-old CF mice.