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. 2013 Jan 17;8(1):e54342. doi: 10.1371/journal.pone.0054342

Table 1. Elevated HBA1 and HBB expression in cervical cancer.

Gene Name Gene Symbol Cervical Cancer Normal Cervix Epithelium Fold Changea P Value
Hemoglobin family
Hemoglobin, alpha HBA 3806.24 2149.13 1.77 0.037
Hemoglobin, beta HBB 3505.32 2364.09 1.48 0.043
Hemoglobin, delta HBD 54.85 63.46 0.86 0.523
Hemoglobin, epsilon 1 HBE1 44.57 44.89 0.99 0.965
Hemoglobin, gamma G HBG2 220.53 192.29 1.15 0.691
Hemoglobin, theta 1 HBQ1 3.75 5.84 0.64 0.006
Hemoglobin, zeta HBZ 1.98 3.43 0.58 0.002
Transcription factors for erythroid differentiation
Nuclear factor (erythroid-derived 2) NFE2 18.09 17.52 1.03 0.946
Kruppel-like factor 1 (erythroid) KLF1/EKLF 37.76 46.48 0.81 0.176
T-cell actue lymphocytic leukemia 1 TAL1/SCL 50.71 61.59 0.82 0.112
GATA binding protein 1 (globin transcriptionfactor 1) GATA1 35 44.92 0.78 0.257
Erythroid cell markers
Spectin, beta, erythrocytic SPTB 65.29 58.93 1.11 0.525
Erythroid-associated factor ERAF 43.95 67.70 0.65 0.007
Aminolevulinate, delta-, synthase 2 ALAS2 6.78 7.28 0.93 0.828
a

Fold-change is calculated based on comparison between cervical cancer and normal cervix epithelium.