Table 1. Elevated HBA1 and HBB expression in cervical cancer.
Gene Name | Gene Symbol | Cervical Cancer | Normal Cervix Epithelium | Fold Changea | P Value | |||||||
Hemoglobin family | ||||||||||||
Hemoglobin, alpha | HBA | 3806.24 | 2149.13 | 1.77 | 0.037 | |||||||
Hemoglobin, beta | HBB | 3505.32 | 2364.09 | 1.48 | 0.043 | |||||||
Hemoglobin, delta | HBD | 54.85 | 63.46 | 0.86 | 0.523 | |||||||
Hemoglobin, epsilon 1 | HBE1 | 44.57 | 44.89 | 0.99 | 0.965 | |||||||
Hemoglobin, gamma G | HBG2 | 220.53 | 192.29 | 1.15 | 0.691 | |||||||
Hemoglobin, theta 1 | HBQ1 | 3.75 | 5.84 | 0.64 | 0.006 | |||||||
Hemoglobin, zeta | HBZ | 1.98 | 3.43 | 0.58 | 0.002 | |||||||
Transcription factors for erythroid differentiation | ||||||||||||
Nuclear factor (erythroid-derived 2) | NFE2 | 18.09 | 17.52 | 1.03 | 0.946 | |||||||
Kruppel-like factor 1 (erythroid) | KLF1/EKLF | 37.76 | 46.48 | 0.81 | 0.176 | |||||||
T-cell actue lymphocytic leukemia 1 | TAL1/SCL | 50.71 | 61.59 | 0.82 | 0.112 | |||||||
GATA binding protein 1 (globin transcriptionfactor 1) | GATA1 | 35 | 44.92 | 0.78 | 0.257 | |||||||
Erythroid cell markers | ||||||||||||
Spectin, beta, erythrocytic | SPTB | 65.29 | 58.93 | 1.11 | 0.525 | |||||||
Erythroid-associated factor | ERAF | 43.95 | 67.70 | 0.65 | 0.007 | |||||||
Aminolevulinate, delta-, synthase 2 | ALAS2 | 6.78 | 7.28 | 0.93 | 0.828 |
Fold-change is calculated based on comparison between cervical cancer and normal cervix epithelium.