Figure 1. Schematic presentation of the possible role and the mechanisms by which MMP-9/uPAR plasmid shRNA (MU-sh) regulate glioma cell migration. ECM, extracellular matrix; ECD, extracellular domain; ICD, intracellular domain; SSAT, spermidine/spermine-N1-acetyl transferase; GC, guanylyl cyclase; NO, nitric oxide; NOS, nitric oxide synthase.