Skip to main content
. 2013 Jan 17;8(1):e54222. doi: 10.1371/journal.pone.0054222

Figure 4. miR-22 is protective against 3-NP toxicity.

Figure 4

Cultured primary striatal neurons (2.5 weeks in vitro) were treated with the indicated concentrations of 3-NP for 48 hours or left untreated (CTRL), and survival of neurons overexpressing miR-22 was compared to neurons not overexpressing miR-22 (uninfected). Cell viability was quantified after immunolabeling for the neuronal marker NeuN. Graphs represent mean ± SEM, n = 15. * represents p-value <0.05, ** represents p-value <0.01, by unpaired t-test.