Figure 3. Significantly deregulated transcription factor networks.

(a) List of sex-biased transcription factors in the zebrafish liver transcriptome. Regulation z-score indicates the degree of enrichment and p value indicates the level of significance. (b) Transcriptional targets network of ppargc1b. (c) Transcriptional targets network of stat4. Female- and male-biased genes are indicated in red and green, respectively. Non-colored genes are not in the sex-biased gene lists but are associated with the sex-biased genes and are introduced by the software to link up the network.