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. 2013 Jan 17;8(1):e53562. doi: 10.1371/journal.pone.0053562

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© 2013 Zheng et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Venn diagram of up-regulated genes in E2-treated males overlapped with sex-biased genes. (b) Venn diagram of down-regulated genes in E2-treated males overlapped with sex-biased genes. (c) Venn diagram of up-regulated genes in KT11-treated males overlapped with sex-biased genes. (d) Venn diagram of down-regulated genes in KT11-treated males overlapped with sex-biased genes . (e) Heat map of expression changes of sex-biased genes in E2- and KT11-treated male livers. For the column corresponding to the sex-biased transcripts, red represents female-biased genes and green represents male-biased genes. For the two columns corresponding to the E2- and KT11-treated male livers, red represents up-regulation and green represents down-regulation. The color intensity is calculated by logarithm-transformed (base 10) p-value. (f) Venn diagram of overlap of up-regulated genes in E2-treated male and down-regulated genes in KT11-treated males. (g) Venn diagram of overlap of down-regulated genes in E2-treated male and up-regulated genes in KT11-treated males. (h) Venn diagram of overlap of up-regulated genes in E2-treated male and up-regulated genes in KT11-treated males. (i) Venn diagram of overlap of down-regulated genes in E2-treated male and down-regulated genes in KT11-treated males.