Table 2. Comparison of haplotype frequencies between patients with autism and healthy controls.
Haplotype | Case (freq) | Control (freq) | P | OR (95%CI) |
Haplotype 1a | ||||
GGC | 268.32 (0.341) | 263.09 (0.304) | 0.083 | 1.201 (0.976–1.478) |
ACC | 220.51 (0.281) | 267.72 (0.310) | 0.235 | 0.879 (0.711–1.087) |
GGT | 169.12 (0.215) | 194.64 (0.225) | 0.690 | 0.954 (0.755–1.205) |
GCC | 113.55 (0.144) | 130.28 (0.151) | 0.775 | 0.961 (0.731–1.262) |
Haplotype 2b | ||||
CA | 344.62 (0.456) | 390.39 (0.478) | 0.394 | 0.916 (0.750–1.120) |
TA | 228.38 (0.302) | 241.61 (0.296) | 0.766 | 1.034 (0.832–1.284) |
TG | 164.62 (0.218) | 166.39 (0.204) | 0.482 | 1.091 (0.856–1.392) |
, Haplotype constructed by rs4446909, rs5989681, and rs6644635;
, Haplotype constructed by rs6588809 and rs28613362; Freq, frequency; OR, odds ratio; CI, confidence interval.