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A, LPS induced plasma corticosterone in naive rats in the absence (n = 7) or the presence of a specific COX-2 inhibitor (NS 398; 3 mg/kg, i.p., n = 6). B, LPS induced fever in the presence or the absence of the specific COX-2 inhibitor in the same animals used for corticosterone measurements *p < 0.05; **p < 0.01; data are mean ± SEM.
