Table 3.

Association of rs7412 and rs429358 in APOE with dementia risk

term	OR (crude)	P (crude)	OR (full)	P (full)
rs7412	0.59, 0.48–0.72	1.87E-07	0.77, 0.63–0.95	1.40E-02
rs429358	0.34, 0.30–0.39	1.51E-67	0.34, 0.31–0.39	3.09E-64
sex	NE	1.49E-04	NE	1.59E-04
age	NE	1.81E-04	NE	1.78E-04

Significance was determined using alternating logistic regression to account for twin dependencies. Odds ratios (ORs) are presented along with 95% confidence intervals. NE = not estimated. Sex and age were included as covariates in crude models.