Table 1. Background characteristics of the 12 patients in whom examination was performed for gene abnormalities.
No | Age | Sex | BI | Histology | T | N | M | Stage | PS | EGFR | EML4-ALK | 1st line | 2nd line | Outcome | Survival time |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 33 | m | 10 | adeno | 4 | 0 | 1 | IV | 1 | + | n.d. | CBDCA+TXL | Gefitinib | death | 1,208 days |
2 | 37 | m | 800 | adeno | 4 | 2 | 1 | IV | 1 | + | n.d. | Gefitinib | CBDCA+TXL | death | 461 days |
3 | 37 | m | 450 | adeno | 4 | 3 | 1 | IV | 3 | + | n.d. | CBDCA+TXL | Gefitinib | death | 379 days |
4 | 39 | m | 400 | adeno | 3 | 3 | 1 | IV | 0 | + | n.d. | CDDP+PEM | Gefitinib | death | 364 days |
5 | 31 | f | 100 | adeno | 1 | 3 | 0 | IIIB | 0 | ± | n.d. | CBDCA+TXL | Gefitinib | alive | 2,688+α |
6 | 35 | f | 0 | adeno | 4 | 0 | 0 | IIIB | 0 | - | + | CBDCA+GEM | PEM | alive | 1,456+α |
7 | 37 | f | 0 | adeno | 2 | 1 | 1 | IV | 0 | - | + | CBDCA+PEM | alive | 757+α | |
8 | 34 | f | 0 | adeno | 4 | 3 | 1 | IV | 2 | - | + | CBDCA+TXL | GEM | death | 568 days |
9 | 33 | m | 300 | adeno | 4 | 3 | 1 | IV | 1 | - | + | CBDCA+TXL | CBDCA+PEM | death | 175 days |
10 | 35 | m | 0 | adeno | 4 | 3 | 1 | IV | 1 | - | + | CBDCA+TXL | CBDCA+PEM | death | 99 days |
11 | 37 | f | 0 | adeno | 2 | 2 | 0 | IIIA | 0 | - | - | CBDCA+TXL | alive | 365+α | |
12 | 36 | m | 340 | non-small | 2b | 3 | 1b | IV | 1 | - | - | CBDCA+TXL | alive | 280+α |
Abbreviations: BI, brinkman index; PS, performance status; ±, EGFR mutaion indeterminate, but responded to gefitinib; n.d., not done; CBDCA, carboplatin; TXL, pacritaxicel; PEM, pemetrexed; GEM, gemcitabine.