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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Affect Disord. 2012 Sep 2;149(0):30–37. doi: 10.1016/j.jad.2012.08.011

Table 2.

Independent main effects of maltreatment and of 5-HTTLPR genotype on depression.

Maltreatment 5-HTTLPR Genotype
Additive Dominant Recessive
Any depression 1.39 (0.68–2.84) 1.35 (0.84–2.19) 1.44(0.65–3.19) 1.58 (0.72–3.46)
Age 8 2.74 (1.05–7.14)* 1.55 (0.80–3.02) 1.25 (0.41–3.78) 2.42 (0.93–6.28)*
Age 8–17.5 1.39 (0.61–3.19) 1.59 (0.91–2.81) 1.66 (0.64–4.30) 2.14 (0.89–5.10)*
Age 18–28 1.38 (0.62–3.09) 1.46 (0.84–2.53) 1.72 (0.66–4.47) 1.64 (0.69–3.90)
Persistent/recurrent 1.94 (0.74–5.10) 1.98 (1.02–3.87)* 1.56 (0.50–4.84) 3.59 (1.34–9.62)**
Single-episode 1.16 (0.50–2.67) 1.00 (0.56–1.76) 1.23 (0.51–3.00) 0.76 (0.27–2.12)

Note: Coefficients represent odds ratios (95% CI); 5-HTTLPR genotype: for Dominant Genetic Model, 0=L/L, 1=L/S or S/S; for Recessive Genetic Model, 0=L/L or L/S, 1=S/S;

*

p (1-tailed)<0.05;

**

p (1-tailed)<0.01.