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Ion Homeostasis gene expression in inner ears of C3H/HeJ mice with inflamed or uninflamed MEs relating to Balb/c controls. Error bars are standard of the mean (SEM). Increased expression of ion homeostasis genes was seen at the highest levels with claudin 3, aquaporins 2, and 3, and gap junction Gjb3, suggesting that chronic middle ear disease leads to altered expression of ion homeostasis and transport functions in the inner ear.
