Table 3.
ME and IE ion Homeostasis Gene Fold Change
| Middle Ear | Inner Ear | |||
|---|---|---|---|---|
| Ion homeostasis | ME uninfected (SEM) | ME infected (SEM) | IE uninfected (SEM) | IE infected (SEM) |
| Slc12a2 | 0.96 (0.16) | 0.88 (0.12) | 4.47 (3.1) | 3.89 (2.4) |
| Atp1b2 | 0.79 (0.08) | 0.43 (0.06) | 3.66 (2.3) | 4.81 (2.8) |
| Atp1b1 | 1.16 (0.13) | 0.59 (0.10) | 1.79 (0.35) | 1.33 (0.25) |
| Clcnka | 2.20 (0.51) | 1.28 (0.40) | 1.87 (0.41) | 4.13 (2.6) |
| Atp1a1 | 1.00 (0.13) | 0.99 (0.17) | 0.90 (0.16) | 0.91 (0.14) |
| Cldn3 | 2.70 (1.2) | 18.20 (8.6) | 2.30 (1.1) | 27.31 (19.5) |
| Cldn4 | 2.55 (0.46) | 6.92 (1.1) | 4.41 (2.3) | 6.91 (3.5) |
| Cldn14 | 1.27 (0.35) | 0.84 (0.34) | 3.31 (0.84) | 6.81 (3.7) |
| Gjb2 | 1.24 (0.11) | 0.84 (0.07) | 1.86 (0.28) | 1.48 (0.22) |
| Gja1 | 1.05 (0.09) | 1.54 (0.23) | 1.18 (0.30) | 1.49 (0.45) |
| Gjb3 | 4.80 (1.7) | 5.91 (2.2) | 0.84 (0.37) | 14.01 (8.7) |
| Gjb6 | 1.33 (0.16) | 0.56 (0.08) | 3.88 (1.1) | 3.23 (0.85) |
| Aqp1 | 0.78 (0.10) | 0.52 (0.04) | 0.93 (0.28) | 1.11 (0.28) |
| Aqp2 | 3.22 (0.47) | 2.79 (0.57) | 5.11 (3.1) | 14.83 (12.9) |
| Aqp3 | 4.38 (2.5) | 5.40 (3.1) | 65.82 (55.6) | 279.74 (202.2) |
| Aqp5 | 1.43 (0.42) | 1.02 (0.12) | 1.69 (0.37) | 4.35 (0.92) |
| Kcne1 | 1.19 (0.37) | 0.46 (0.12) | 2.61 (0.57) | 3.39 (1.2) |
| Kcnq1 | 1.15 (0.18) | 0.75 (0.21) | 2.14 (0.49) | 2.42 (0.63) |
| Kcnq4 | 1.22 (0.28) | 0.48 (0.15) | 1.60 (0.25) | 1.50 (0.30) |
| Kcnj10 | 0.83 (0.14) | 0.41 (0.10) | 1.20 (0.18) | 1.11 (0.12) |
| Scnn1α | 1.60 (0.22) | 0.83 (0.14) | 1.31 (0.22) | 2.07 (0.50) |
| Scnn1β | 1.72 (0.26) | 0.79 (0.23) | 1.66 (0.40) | 2.55 (1.0) |
| Scnn1γ | 3.11 (0.65) | 1.69 (0.62) | 1.09 (0.50) | 5.88 (3.7) |
| Tmprss3 | 0.63 (0.10) | 0.27 (0.06) | 1.20 (0.23) | 1.28 (0.50) |
SEM (standard error of the mean); Values in bold show fold change >2x or <0.5x control