Figure 1.

Regulatory networks of transcriptional regulators, SOHLH1, SOHLH2, NOBOX, LHX8 and FIGLA (Modified from Choi and Rajkovic [5]). Black line, direct regulation; Blue line, putative regulation; ZP, zona pellucida; GDF9, growth differentiation factor 9; POU5f1, POU class 5 homeobox 1; PAD6, peptidyl arginine deiminase type VI; OOG1, oogenesin 1; cMOS, moloney sarcoma oncogene; ZAR1, zygote arrest 1; OOSP1, oocyte secreted protein 1; NPM2, nucleoplasmin 2; DMRT1, doublesex and mab-3 related transcription factor 1; STRA8, stimulated by retinoic acid gene 8; CASP, caspase; BAX, BCL2-associated X protein; KITL, kit ligand; TDRD, tudor domain containing; OAS1, 2'-5' oligoadenylate synthetase 1; EXO1, exonuclease 1; NLRP, NLR family, pyrin domain containing; DPPA3, developmental pluripotency-associated 3; H1foo, H1 histone family; member O, oocyte-specific.